The human lysosome gene database
WebOpen table in a new tab. To investigate the cellular stress-induced transactivation of these non-TFEB–regulated genes, human lung carcinoma A549 and cervical cancer HeLa cells … WebApr 15, 2024 · The GO analysis is a commonly used approach providing functional studies of large-scale genomic or transcriptomic data. 24 Kyoto Encyclopedia of Genes and Genomes (KEGG) database collects the pathway-related information about how molecules are networked. 25 In the present study, the GO functional analysis comprising three ontology …
The human lysosome gene database
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WebLysosome-associated membrane protein 2 ( LAMP2 ), also known as CD107b ( C luster of D ifferentiation 107b) and Mac-3, is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins . The protein encoded by this gene is a member of a family of membrane glycoproteins. WebAug 26, 2024 · The genes profiled were those reported on the Human Autophagy Database 39 and Human Lysosome Gene Database 40, as well as PD risk genes, which have been …
WebHere, we summarize our current knowledge of the regulation of lysosome by G4 ligands, underlying their potential functional impact on lysosome biology and autophagic flux, as well as on the transcrip- tional regulation of lysosomal genes. We outline the consequences of these effects on cell fate decisions and we systematically analyzed G4-prone ... WebFeb 1, 2007 · It is reported that the gene encoding the Drosophila ortholog of the HPS5 subunit of BLOC‐2 is identical to the granule group gene pink (p), which was first studied in 1910 but had not been identified at the molecular level. Lysosome‐related organelles comprise a group of specialized intracellular compartments that include melanosomes …
Web15 rows · LYSOSOME: Systematic name: M13845: Brief description: Genes annotated by the GO term GO:0005764. ... WebThe Lysosome Gene Database is an ongoing effort to catalogue genes encoding lysosomal proteins. For each lysosomal gene, LGDB provides information on : miRNA-genes interactions master gene transcription factor EB (TFEB) CLEAR binding motif and binding … The Lysosome Gene Database. Help. Two types of queries can be made: ... By … The Lysosome Gene Database is an ongoing effort to catalogue genes … The Mouse Lysosome Gene Database. The Lysosome Gene Database is an ongoing …
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WebCELL LINE TYPES. The 1055 different cell lines used in the Cell Line section have been selected to represent various cell populations in different tissue types and organs of the human body. Most of the cell lines used are human cancer cell lines (n = 985). In addition to the cancer-derived cell lines, there is a number of cell lines that have ... hindustan jharkhandWebThe expression of genes was determined with Illumina Human HT-12 V3 bead chips (Illumina, San Diego, CA, USA). In order to estimate significantly differentially expressed … fa bsbWebJun 7, 2024 · Lysosomes are degradation centers and signaling hubs in cells and play important roles in cellular homeostasis, development, and aging. Changes in lysosome function are essential to support cellular adaptation to multiple signals and stimuli. Therefore, lysosome biogenesis and activity are regulated … Lysosome biogenesis: … fabsalesWebMar 25, 2024 · For any given gene list, the Database for Annotation, Visualization ... there were only 12 genes common between the training and validation lysosome gene list but both of the training gene-sets networks found ... S2 Fig. Expression of mTOR and its associated genes in cultures of glucose treated human proximal tubular cells. Human … fabs matlabWebMar 14, 2024 · Lysosomal acid lipase (LAL), encoded by the lipase A (LIPA) gene in human, is the only known enzyme active at an acidic pH in the lysosome that hydrolyzes cholesteryl esters (CEs) and triglycerides.The … hindustan jindabadWebThe Human Lysosome Gene Database (hLGDB) is the first searchable database focused on the census of genes be-longing to the lysosomal system and on their regulation by miRNAs. No database resources entirely dedicated to the regulation of lysosomal genes by miRNAs or other regu-lators are currently available. Several lists of lysosomal hindustan ka jhanda ka photoWebJun 25, 2009 · We found that most lysosomal genes exhibit coordinated transcriptional behavior and are regulated by the transcription factor EB (TFEB). Under aberrant lysosomal storage conditions, TFEB translocated from the cytoplasm to the nucleus, resulting in the activation of its target genes. fabs ltd