WebbEarly thalamus-independent steps in the process of cortical arealization take place on the basis of information intrinsic to the cortical primordium, as proposed by Rakic in his classical protomap hypothesis [Rakic, P. (1988)Science, 241, 170-176]. These steps depend on a dense network of molecular … WebbInvestigating the protomap hypothesis in the primate cerebral cortex; EPH A receptor expression The cerebral cortex, the seat of consciousness and intelligence, is mapped out into functional areas; for instance vision, movement control and language are controlled by distinct areas that are the same across normal individuals.

Spatiotemporal Differences in the Regional Cortical Plate and …

Webb24 jan. 2024 · This hypothesis predicts that category-selective responses will emerge in regions of cortex that correspond to overlapping protomap features. For example, because faces tend to be foveated and have substantial low spatial frequency and curvilinear content, the FFA will develop in a region of the protomap that responds preferentially to … Webb27 feb. 2024 · The protomap hypothesis suggests that the regional destiny of cortical neurons and the relative size of the cortical area are genetically determined early during embryonic development. The protocortex hypothesis suggests that the regional growth rate is predominantly shaped by external influences. crachat sang estomac

(PDF) Charting the protomap of the human telencephalon

WebbAccording to the protomap hypothesis formulated by Rakic neural progenitors in the ventricular zone form a mosaic of proliferative units that provide a primordial species-specific cortical map. The Protomap is a primordial molecular map of the functional areas of the mammalian cerebral cortex during early embryonic development, at a stage when neural stem cells are still the dominant cell type. The protomap is a feature of the ventricular zone, which contains the principal cortical progenitor cells, known as radial glial cells. Through a process called 'cortical patterning', the protomap is patterned by a system of signaling centers in the embryo, which provide positional i… WebbThis hypothesis is in agreement with the protomap hypothesis (the CP or SP areal destiny and size are determined early during fetal development). Our second hypothesis was that within periods there are significant differences in the relative growth rate (i.e., percent increase per GW) between neighboring regions. crachat rose