WebApr 24, 2024 · Both MC38 and Pan02 cell lines displayed dependence on xCT, as deletion of xCT rendered cells unable to proliferate in vitro (Fig. 1 H and I). Compared with their WT counterparts, xCT-deficient tumor cells exhibited variable but significant decreases in viability, with the exception of Pan02 clone 1-5 ( SI Appendix , Fig. S1 A and B ). WebThe PDAC cell line (PAN02 cells; DCTD Tumor Repository, NCI-Frederick, Frederick, MD) was cultured and expanded in Dulbecco’s modified Eagle’s medium (DMEM; Nacalai Tesque, Kyoto, Japan) supplemented with 10% heat-inactivated fetal bovine serum and 100 µg/mL penicillin and streptomycin (P/S; Life Technologies, Carlsbad, California, USA).
PD‐L1 blockade enhances response of pancreatic ductal …
WebMouse pancreatic (Pan02) cells, mouse colon (CT26) cells, mouse mammary carcinoma (4T1) cells, mouse melanoma (B16-F10) cells and the human acute lymphoblastic … WebPan02 is a well-established mouse pancreatic ductal adenocarcinoma (PDAC) model developed by chemical induction with 3-methylcholanthrene (3-MCA) (1). The cell line … promotionsstudium rwth
PD-L1-directed PlGF/VEGF blockade synergizes with …
WebDescription. The mouse Panc02 is a well-established mouse pancreatic epithelial cell line, derived from adenocarcinoma model developed by chemical induction with 3-MCA (3-methylcholanthrene) in male C57BL/6 mice.It is used as pancreatic cancer models for drug development and clinical research. Gentarget generated this GFP reporter cells, t … WebFeb 23, 2024 · PAN02was purchased from the National Infrastructure of Cell Line Resource (Beijing). All cells were cultured at 37 °C in a humidified incubator with 5% CO 2 in Dulbecco’s modified Eagle’s medium (DMEM) (HyClone) supplemented with 10% fetal bovine serum (FBS) (HyClone), 100 U/mL penicillin, and 100 μg/mL streptomycin (Gibco). WebFigure Legend Snippet: (A) Nude mice carrying Pan02 cell tumor xenografts in the flanks were administered curcumin intraperitoneally for 3 weeks. There was a significant reduction in tumor size from curcumin-treated animals when compared to untreated controls (*p0.05).(B) Curcumin treatment resulted in significantly lower tumor weight when … promotionsstudiengang wwu