Human ether-a-go-go-related gene
WebCommon Pharmacophores for Uncharged Human Ether-a-go-go-Related Gene (hERG) Blockers. Journal of Medicinal Chemistry 2006, 49 (23) , 6917-6921. DOI: 10.1021/jm060500o. Andrea Cavalli,, Paolo Carloni, and, Maurizio Recanatini. Target-Related Applications of First Principles Quantum Chemical Methods in Drug Design. http://www.medchem4410.seesaa.net/article/131746664.html
Human ether-a-go-go-related gene
Did you know?
WebSci-Hub Molecular Determinants of Human ether-a-go-go-Related Gene 1 (hERG1) K+ Channel Activation by NS1643. Molecular Pharmacology, 79 (1), 1–9 10.1124/mol.110.067728 sci hub to open science ↓ save Grunnet, M., Abbruzzese, J., Sachse, F. B., & Sanguinetti, M. C. (2010). WebThe human ether-a-go-go related gene (hERG) encodes the inward rectifying voltage gated potassium channel in the heart (I Kr) which is involved in cardiac repolarization. …
hERG (ヒト遅延整流性カリウムイオンチャネル遺伝子, human Ether-a-go-go Related Gene) とは、心筋活動電位の再分極を担う、 カリウムイオンチャンネルKv11.1をコードする遺伝子である。 Web28 sep. 2007 · Abstract. Antipsychotic drugs are thought to exert their therapeutic action by antagonizing dopamine receptors but are also known to produce side effects in the heart by inhibiting cardiac ether-a-go-go–related gene (ERG) K + channels. Recently, it has been discovered that the same channels are present in the brain, including midbrain dopamine …
Webhuman Ether-a-go-go Related Gene) ist ein spannungsaktivierter, auswärtsgleichrichtender Kaliumkanal in Herzmuskelzellen und ... Das Gen ist verwandt mit dem bei Drosophila … Web25 apr. 2024 · 感谢您对公司的关注！. 在心肌细胞中，hERG（human Ether-a-go-go Related Gene）是编码心脏钾离子通道蛋白的基因，该蛋白介导一种延迟整流钾电流。. …
WebAN OVERVIEW ON HUMAN ETHER-A-GO-GO-RELATED GENE ASSAY Abstract hERG (human ether-à-go-go-related gene) encodes a potassium ion channel which involved …
Web5 mei 2008 · May 5, 2008. #2. "Ether-a-go-go" is part of the name of of the hERG (a gene). hERG stands for " h uman E ther-a-go-go R elated G ene." Here's the explanation from … spata neighborhood athensWeb21 aug. 2015 · The human ether-a-go-go-related gene (hERG) encodes the pore-forming subunit of the rapidly activating delayed rectifier potassium channel (IKr). A reduction in the hERG current causes long QT syndrome, which predisposes affected individuals to ventricular arrhythmias and sudden death. technics 1200 isolation feetWeb21 aug. 2015 · Introduction. The human ether-a-go-go-related gene (hERG) encodes the pore-forming subunit of the rapidly activating delayed rectifier potassium channel (I Kr), … technics 1200 footWebWe previously demonstrated that the activation of integrins containing the beta (1) subunit leads to a selective increase in potassium currents carried by the human ether-a-go-go-related gene (hERG) channels in neuroblastoma and leukemia cells; this current activation modulates adhesion-dependent differentiation in these cells. technics 1200 tonearm assemblyWeb14 okt. 2012 · hERG的全称是human ether-a-go-go related gene。它是从人的海马神经中分离出来的基因。hERG基因编码形成电压激活延迟内向整流的钾离子通道（Ikr）,大量分 … technics 1200 mk2 maintenanceWeb1 jan. 2005 · Electrical activity in the human heart is controlled by the movement of ions into and out of individual cardiac cells. Voltage-dependent ion channels are the membrane-spanning proteins that allow this ionic movement to occur during each heartbeat. technics 1200 for sale usedWeb1 okt. 2024 · Amongst various ion channels in the heart, the human ether-à-go-go-related gene (hERG) channel is an important off-target for drugs that induce cardiotoxicity. … technics 1210 gae