WebApr 16, 2024 · Then, further analysis of hub genes using the GEPIA tool and Kaplan-Meier curves that showed upregulation of CDK1 and PRC1 is associated with better survival, … WebOct 7, 2024 · Despite recent advances in the prevention of cervical cancer, the disease remains a leading cause of cancer-related deaths in women worldwide. ... Tp*C subset …
Identification of Novel Genes and Associated Drugs in …
WebBackgroud: Human papillomavirus type 16 (HPV16) is a high-risk HPV subtype and a potent carcinogen. The HPV16 E6 and E7 genes are considered oncogenes that play a core role in the development of cervical cancer. Methods: In the current study, we enrolled 97 HPV16-positive cervical cancer patients (case group) and 136 HPV16-positive asymptomatic … WebThis study investigated key ubiquitination-related genes associated with cervical cancer. We downloaded standardized gene expression profiles (GSE39001, GSE63514, GSE52903, GSE9750, GSE6791, and GSE7803) to analyze differentially expressed genes (DEGs) between the tumor and normal samples. By comparing with ubiquitination … cool fact about volcanoes
Polymorphisms in endoplasmic reticulum aminopeptidase genes …
WebNov 9, 2024 · Cervical cancer is the fourth most common cancer in females, with 604,127 new cases and 341,831 deaths estimated for 2024 worldwide . Squamous cell carcinoma ... primarily by keratinocytes, gradually replaced by abnormal epithelial cells in malignant transformation. Although Th17-associated cytokine genes (IL17A and IL17F) ... WebThe functional inactivation of TP53 and Rb tumor suppressor proteins by the HPV-derived E6 and E7 oncoproteins is likely an important step in cervical carcinogenesis. We have previously shown siRNA technology to selectively silence both E6/E7 oncogenes and demonstrated that the synthetic siRNAs could specifically block its expression in HPV … WebWe searched PubMed and the GWAS Catalog with the terms “cervical cancer” OR “cervical ... cool fact for the day