WebSep 15, 2024 · In addition, the participation of transcription mediated by CREB has been widely analyzed in the memory process and AD development. Designing pharmacologic or genetic therapeutic approaches based on the targeting of CREB-BDNF signaling could be a promising treatment potential for AD. In this review, we summarize data demonstrating … WebCREB (top) is a transcription factor capable of binding DNA (bottom) and regulating gene expression. CREB-TF (CREB, cAMP response element-binding protein) [1] is a cellular transcription factor. It binds to certain DNA sequences called cAMP response elements (CRE), thereby increasing or decreasing the transcription of the genes. [2]
The role of CREB and BDNF in neurobiology and treatment of ... - PubMed
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