WebThe CpG-ODN adjuvant generates Th1-dominated type, CD8 + T-lymphocyte and CTL immune responses which are necessary for the protective immunity against toxoplasmosis. 47,48 Results of the present study have shown that addition of CpG-ODN adjuvant significantly improves the efficiency of pVitro-SAG1-GRA7 vaccines; similarly to results … WebDue to its strong immune stimulatory effects through TLR9, CpG-containing oligodeoxynucleotides (CpG ODN) have been tested in multiple clinical trials as vaccine adjuvant for infectious diseases and cancer. However, immune suppression induced by
CpG ODN 2006 FITC Labeled hTLR9 Ligand InvivoGen
WebNational Center for Biotechnology Information WebJun 25, 2012 · A specific oligodeoxynucleotide (ODN), ODN MT01, was found to have positive effects on the proliferation and activation of the osteoblast-like cell line MG 63. In this study, the detailed signaling pathways in which ODN MT01 promoted the differentiation of osteoblasts were systematically examined. ODN MT01 enhanced the expression of … lance reddick mass effect
The effect of polyclonal activators on rabbit B cell antibody ...
WebJan 14, 2024 · Drug Profile Agatolimod - Pfizer Alternative Names: Agatolimod sodium; CpG 7909; CPG ODN 2006; CpG oligodeoxynucleotide 7909; PF-3512676; PF-676; ProMune Latest Information Update: 14 Jan 2024 Price : $50 * Buy Profile Adis is an information provider. We do not sell or distribute actual drugs. WebJan 23, 2024 · After incubation, antibody production was induced by adding 10 µg/mL of his tagged H-OspA (antigen). Cells were incubated for 24 h before adding 0.25 µM Class B CpG oligonucleotide ODN 2006 (InVivoGen, strong activator of B lymphocytes with weak stimulation of IFN-α secretion) to each well, and the incubation was continued until 72 h. WebFeb 2, 2012 · The mechanism by which CpG treatment reduced the ability of MDSC to suppress T cell activation was investigated. mMDSC were isolated from the spleens of tumor bearing mice and cultured in vitro with CpG or control ODN for 48 hr. Cell surface staining of CpG-treated cultures revealed that their expression of F4/80 increased by 3-fold while ... help linspace