WebCurcumin is a naturally occurring compound derived from turmeric. Despite its many medicinal properties, such as being an antioxidant, anti-inflammatory, tumor reducer, etc., applications of curcumin are restricted due to its low aqueous solubility and consequently its poor bioavailability. By converting the solid state of poorly water-soluble active … WebIn addition, the coamorphous tadalafil–repaglinide showed improved stability compared to the pure amorphous forms under long-term stability and accelerated storage conditions as well as under high compressing pressure. In conclusion, this study showed that co-amorphization technique is a promising approach for improving the dissolution rate ...
Effect of drug-coformer interactions on drug dissolution from …
WebJan 9, 2024 · It has diverse pharmacological action but low oral solubility and bioavailability continue to limit its use as a drug. With the aim of improving the bioavailability of … WebNov 11, 2024 · The formation of cocrystal imparts thermal stability to the parent compound. The melting point of the cocrystal was reported to be 120 ° C, whereas the melting point of chloral hydrate is 60 ° C. In the cocrystal, chloral betaine exists as a charge-assisted diol-carboxylate heterodimer, with further Cl …. goonies location tour
Cocrystal and Coamorphous Solid Forms of Enzalutamide …
WebJul 11, 2014 · The phenomenon of cocrystallization, which encompasses the art of making multicomponent organic solids such as cocrystals, solid solutions, eutectics, etc. for novel applications, has been less studied in terms of reliably and specifically obtaining a desired cocrystallization product and the issues that govern their formation. Further, the design, … WebI am a research scientist with over 6+ years of experience in pharmaceutical crystallization and crystal engineering. My expertise lies in solid-form screening of APIs, including polymorph screening, cocrystal/salts, solvate, amorphous, eutectic mixture, and solid solution, as well as their control and characterization. In addition, I have experience in … WebInfluence of Excipients on Cocrystal Stability and Formation crystal growth and design 25 مايو، 2024 The Very Different Effect of Water on Nucleation, Crystallization and Hydrate Stability of Zingerone and Vanillate Esters ... Investigation of the formation of drug-drug cocrystals and coamorphous systems of the antidiabetic drug gliclazide goonies martha plimpton