WebAbstract. Circulating neuron-specific enolase (NSE) and chromogranin A (CgA) were measured in 128 patients with neuroendocrine tumours (NET) to compare their sensitivity and specificity, to investigate factors associated with elevated serum levels and to determine the usefulness of these markers in the follow-up of NET patients. WebTypically, chromogranin A levels are around 2.5 times higher with the LC/MS/MS assay—this relationship is captured by the following equation: ELISA result = 13.6 + 0.36 …
Chromogranin a levels in diagnosis, treatment and follow-up of …
WebChromogranin A is a protein stored and released with peptides and amines in a variety of neuroendocrine tissues. The plasma level of chromogranin A in patients with neuroendocrine tumors has a sensitivity and specificity of 75% and 84%, respectively. Chromogranin A levels increase with tumor burden. WebEvery laboratory has a specific range that will be classified as normal for them. In general, however, the normal range for CgA is 1.9-15 ng/mL. Anything above this may be an indication of the presence of a tumor. … the gift billy bob thornton
Carcinoid Tumor Johns Hopkins Medicine
WebAug 1, 1997 · Serum levels of CgA, neuron-specific enolase (NSE), and the α-subunit of glycoprotein hormones (α-SU) were determined in 211 patients with neuroendocrine tumors and 180 control subjects with nonendocrine tumors. ... CHROMOGRANIN A (CgA) is a protein that is present in the secretory dense core granules of neuroendocrine tissues . It … WebSep 21, 2016 · Chromogranin A (CgA) is an acidic glycoprotein with a molecular mass of 49 kd that is widely expressed by neuroendocrine cells and constitutes one of the most abundant components of secretory granules. 1 CgA is physiologically released by exocytosis and may be detected in the blood. WebTypically, chromogranin A levels are around 2.5 times higher with the LC/MS/MS assay—this relationship is captured by the following equation: ELISA result = 13.6 + 0.36 × LC/MS/MS result; correlation coefficient = 0.71. Reference intervals … the gift biz